Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on comfort, location and traveller experience. Last updated on .
Cape Girardeau Hotel Accommodation
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Top 5 hotels in Cape Girardeau at a glance
- Drury Plaza Hotel Cape Girardeau Conference Center — 3-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG — 2.5-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
- Drury Inn & Suites Cape Girardeau — 3-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
- Pear Tree Inn Cape Girardeau West — 2.5-star hotel in Cape Girardeau. Guest rating: 9.0/10 — Wonderful.
- Hampton Inn Cape Girardeau I 55 East — 2.5-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
Where to stay in Cape Girardeau?




Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center



Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG



Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau



Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West



Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East



Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown



Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau



Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau



Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG



Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau North



Town House Inn Cape Giradreau
Town House Inn Cape Giradreau



Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO



La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau



Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau



EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelGet last-minute hotel deals in Cape Girardeau and save more




Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center



Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG



Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown



Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCheck out pet-friendly hotels in Cape Girardeau




Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterYou may also like hotels with pools in Cape Girardeau




Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG



Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center



Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauGo beyond your typical stay in Cape Girardeau
Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Top landmarks in Cape Girardeau

Southeast Missouri State University

Riverfront Bridge Park
Century Casino & Hotel Cape Girardeau
Riverfront Park
Cape Splash Family Aquatic Center
Hunter Valley Winery
Cape Rock Park
Show Me Center
Learn more about Cape Girardeau
Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.
See all hotels in Cape Girardeau
Check out reviews of Cape Girardeau hotels guests love
Town House Inn Cape Giradreau
"Its always a peaceful stay for me 💗"
Tru By Hilton Cape Girardeau
"Super clean hotel with a very friendly staff."
Candlewood Suites Cape Girardeau by IHG
"Our stove had a short in it so I wasn’t able to cook"
Drury Plaza Hotel Cape Girardeau Conference Center
"Everything about this property is 1000000/100000"
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
"Very nice hotel and staff. Would definitely recommend "
Drury Inn & Suites Cape Girardeau
"Everything was awesome, highly recommended this hotel"
Hampton Inn Cape Girardeau I 55 East
"Good Job!"
Fairfield Inn & Suites by Marriott Cape Girardeau
"I had a great stay! Everything looked new and well maintained. The room was very clean, comfortable, and inviting. The hotel's location was perfect—it was close to everything I needed, which made getting around easy. I would definitely stay here again and recommend it to anyone visiting the area."
Frequently asked questions
Find out more about Cape Girardeau
Explore Cape Girardeau: Where River Serenity Meets Floral Splendor and Academic Vibrance
Nestled along the banks of the mighty Mississippi River, Cape Girardeau, Missouri, is a hidden gem that beautifully blends history, nature, and culture. Stroll through the charming downtown, where historic architecture meets vibrant art galleries and delightful eateries. Explore the scenic Riverfront Park, perfect for leisurely walks, picnics, and stunning river views. Don’t miss the Cape Riverfront Market for local produce and crafts. For sports enthusiasts, the Cape Girardeau Sportsplex offers various activities. With its welcoming atmosphere and rich heritage, Cape Girardeau invites you to experience a delightful blend of small-town charm and captivating adventures.
4 tips for savvy savings when booking a hotel in Cape Girardeau
- Book for the cheapest times: The most budget-friendly time to visit Cape Girardeau is during January, November, and December, when hotel prices are generally lower. For an affordable experience that allows you to soak in the region's historical and cultural highlights, a stay of at least 2 to 3 days is recommended. This will give you ample time to explore key landmarks, such as the river, as well as enjoy family-friendly activities, historical sites, and the vibrant dining and shopping scene. You'll also appreciate the friendly locals and the charming atmosphere, making your visit truly great value for money.
- Look for last-minute deals on Hotels.com: To uncover affordable hotel options in Cape Girardeau, start by exploring the DealsOpens in a new window or Last-Minute Deals sections on Hotels.com, where you may discover discounted rates as your travel date approaches. Consider enabling email alerts or push notifications to keep informed about flash sales and special last-minute offers, ensuring you don’t miss potential savings. Additionally, the Smart Shopping tool in the app allows you to compare hotel prices and amenities, helping you make informed choices. This way, if prices drop or rooms become available, you're more likely to see these updates first, making your last-minute getaway planning easier.
- Be flexible with dates: Prices can fluctuate depending on factors like the hotel's location, star rating, and the time of year. Being flexible with your travel dates could help you potentially save on your stay at a hotel in Cape Girardeau. If you're after a unique experience, boutique hotels often provide a more personalised touch and may offer better value. When you book through Hotels.com, we’ll inform you whether the price for your chosen dates is above or below the average. If the price leans towards the higher end, we’ll suggest alternative dates that could be more affordable, helping you to secure a better deal.
- Consider your location: Hotels close to the city centre usually tend to be more expensive, but with Cape Girardeau's excellent public transport connections, you may discover a more affordable independent hotel a bit further out that is still well connected. For those keen to explore alternative, less crowded neighbourhoods or even some lesser-known nearby towns, there is often great value for money to be found. Opting for these alternative destinations could provide a more authentic and budget-friendly experience.
Best time to go to Cape Girardeau
Cape Girardeau experiences its lowest average temperature in January, at 34.9°F (1.6°C), while July is the hottest month, with an average temperature of 79.2°F (26.2°C). April tends to be the wettest month. The peak travel months to visit Cape Girardeau are April, June, and July, which see a higher number of tourists. During this peak period, the weather is mostly sunny, accompanied by light rainfall. In contrast, January, October, and December are ideal if you're looking for a calmer vacation, marked by light rainfall and mostly sunny conditions.
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