Cape Girardeau Hotel Accommodation

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Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Where to stay in Cape Girardeau?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on quality, location and traveller experience. Last updated on .

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
NZ$201
includes taxes & fees
18 Oct - 19 Oct
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

2. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
NZ$181
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites Cape Girardeau
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

3. The Riverview

The Riverview
Cape Girardeau
NZ$218
includes taxes & fees
15 Oct - 16 Oct
The Riverview
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

4. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
NZ$205
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A lobby with seating areas, a reception desk, and a bar.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

5. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
NZ$253
includes taxes & fees
25 Oct - 26 Oct
Courtyard by Marriott Cape Girardeau Downtown
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
An outdoor patio with stone walls, wicker furniture, and large windows.

6. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
NZ$213
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Cape Girardeau I 55 East
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

7. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
NZ$203
includes taxes & fees
18 Oct - 19 Oct
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

8. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
NZ$145
includes taxes & fees
25 Oct - 26 Oct
Pear Tree Inn Cape Girardeau West
A modern retail area with a display of local items and snacks.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
NZ$181
includes taxes & fees
25 Oct - 26 Oct
Tru By Hilton Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
NZ$175
includes taxes & fees
25 Oct - 26 Oct
Candlewood Suites Cape Girardeau by IHG
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
NZ$120
includes taxes & fees
1 Nov - 2 Nov
Quality Inn Cape Girardeau North
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A bathroom with a marble wall and a white bathtub.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
NZ$146
includes taxes & fees
13 Oct - 14 Oct
Town House Inn Cape Giradreau
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
An outdoor patio with tables and chairs, a stone wall, and large windows.

13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
NZ$156
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.
A hotel room with two beds, a brick wall, and a wooden headboard.

14. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
NZ$151
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites Jackson MO
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.
A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.
A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.
A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

15. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
NZ$146
includes taxes & fees
2 Nov - 3 Nov
Comfort Suites Jackson-Cape Girardeau
A living room with a blue wall, a fireplace, a sofa, and a chair.
A bar area with stools and a counter where a bartender is serving drinks.
A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.
A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

16. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
NZ$204
includes taxes & fees
13 Oct - 14 Oct
EC Reed's Mercantile and Hotel
A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.
A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.
A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.
A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

17. Town House Inn

Town House Inn
Jackson
NZ$137
includes taxes & fees
13 Oct - 14 Oct
Town House Inn
A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.
A rustic building with a thatched roof, surrounded by dense greenery and a gravel path leading to it.
A cozy living room with a brown leather sofa, a wooden coffee table, and a window with a view of trees.
A stone building with a patio area, string lights, and outdoor seating.

18. Makanda Inn

Makanda Inn
Makanda
NZ$521
includes taxes & fees
13 Oct - 14 Oct
Makanda Inn
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A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
NZ$560
for 2 nights, 1 room
NZ$280 per night
includes taxes & fees
Candlewood Suites Cape Girardeau by IHG
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
NZ$830
for 2 nights, 1 room
NZ$415 per night
includes taxes & fees
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
NZ$743
for 2 nights, 1 room
NZ$372 per night
includes taxes & fees
Drury Inn & Suites Cape Girardeau
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
NZ$746
for 2 nights, 1 room
NZ$373 per night
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
An outdoor patio with stone walls, wicker furniture, and large windows.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
NZ$705
for 2 nights, 1 room
NZ$352 per night
includes taxes & fees
Hampton Inn Cape Girardeau I 55 East
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
NZ$607
for 2 nights, 1 room
NZ$303 per night
includes taxes & fees
Pear Tree Inn Cape Girardeau West
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A bathroom with a marble wall and a white bathtub.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
NZ$291
for 2 nights, 1 room
NZ$146 per night
includes taxes & fees
Town House Inn Cape Giradreau
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
NZ$819
for 2 nights, 1 room
NZ$409 per night
includes taxes & fees
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
NZ$434
for 2 nights, 1 room
NZ$217 per night
includes taxes & fees
Quality Inn Cape Girardeau North
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A lobby with seating areas, a reception desk, and a bar.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
NZ$1,207
for 2 nights, 1 room
NZ$603 per night
includes taxes & fees
Courtyard by Marriott Cape Girardeau Downtown
A modern retail area with a display of local items and snacks.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
NZ$711
for 2 nights, 1 room
NZ$355 per night
includes taxes & fees
Tru By Hilton Cape Girardeau
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.
A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

The Riverview

The Riverview
Cape Girardeau
The Riverview

Check out pet-friendly hotels in Cape Girardeau

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
NZ$145
includes taxes & fees
25 Oct - 26 Oct
Pear Tree Inn Cape Girardeau West
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
NZ$201
includes taxes & fees
18 Oct - 19 Oct
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
NZ$181
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites Cape Girardeau
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
An outdoor patio with stone walls, wicker furniture, and large windows.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
NZ$213
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Cape Girardeau I 55 East
A modern retail area with a display of local items and snacks.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
NZ$181
includes taxes & fees
25 Oct - 26 Oct
Tru By Hilton Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
NZ$175
includes taxes & fees
25 Oct - 26 Oct
Candlewood Suites Cape Girardeau by IHG
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A bathroom with a marble wall and a white bathtub.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
NZ$146
includes taxes & fees
13 Oct - 14 Oct
Town House Inn Cape Giradreau
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You can also stay at hotels with a pool in Cape Girardeau

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
NZ$201
includes taxes & fees
18 Oct - 19 Oct
Drury Plaza Hotel Cape Girardeau Conference Center
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
NZ$181
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites Cape Girardeau
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
NZ$205
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
NZ$203
includes taxes & fees
18 Oct - 19 Oct
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
An outdoor patio with stone walls, wicker furniture, and large windows.

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
NZ$213
includes taxes & fees
18 Oct - 19 Oct
Hampton Inn Cape Girardeau I 55 East
A modern retail area with a display of local items and snacks.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
NZ$181
includes taxes & fees
25 Oct - 26 Oct
Tru By Hilton Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
NZ$175
includes taxes & fees
25 Oct - 26 Oct
Candlewood Suites Cape Girardeau by IHG
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
NZ$120
includes taxes & fees
1 Nov - 2 Nov
Quality Inn Cape Girardeau North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in Cape Girardeau are cheapest in December
Price trends for hotels in Cape Girardeau
Pricing is based on two traveller single night rates
View properties in October
Typical weather for Cape Girardeau
October
High 21°C / low 11°C. Sunny most days.
View properties in October
21°
11°
13°
4°
9°
1°
6°
-2°
8°
-1°
14°
5°
19°
9°
25°
15°
30°
20°
32°
21°
31°
20°
28°
17°
Monthly weather averages (˚C)

Top landmarks in Cape Girardeau

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
If you'd like to get a taste of Cape Girardeau student life, check out Southeast Missouri State University, located 0.9 mi (1.4 km) from central Cape Girardeau.
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A cable-stayed bridge over a river with a rocky shoreline in the foreground.

Riverfront Bridge Park

8.8/10 (129 reviews)
Riverfront Bridge Park is worth a visit, located 0.7 mi (1.1 km) from central Cape Girardeau.
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Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)
Century Casino & Hotel Cape Girardeau is 0.5 mi (0.8 km) from central Cape Girardeau, why not stop by during your stay?
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Hunter Valley Winery

7.4/10 (48 reviews)
Travellers might want a tour of Hunter Valley Winery, just one of the places to visit, located 9.3 mi (14.9 km) from central Cape Girardeau.
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Riverfront Park

8.0/10 (2 reviews)
Riverfront Park is worth a visit when in central Cape Girardeau.
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Show Me Center

8.6/10 (40 reviews)
You can catch an event at Show Me Center, located 1.1 mi (1.8 km) from central Cape Girardeau.
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Cape Splash Family Aquatic Center

8.6/10 (21 reviews)
Why not give yourself a treat with a trip to Cape Splash Family Aquatic Center, one of the family attractions located 3.1 mi (5.1 km) from central Cape Girardeau? If you have fun at Cape Splash Family Aquatic Center, you'll love Cape Girardeau Conservation Nature Center, located nearby.
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Cape Rock Park

8.6/10 (36 reviews)
Cape Rock Park is worth a visit, located 1.9 mi (3.1 km) from central Cape Girardeau.
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Learn more about Cape Girardeau

Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Centre or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic city centre invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

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A nighttime view of a bridge with its cables illuminated against a starry sky.

Check out reviews of Cape Girardeau hotels guests love

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Room was clean, staff was courteous and helpful. Breakfast was good, nice spread."
Darnetta 1-night trip
Posted 2 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"The hotel was very clean and nice. The beds were very comfortable. I would stay again"
PAT 2-night trip
Posted 2 hours ago
Pear Tree Inn Cape Girardeau West
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

10/10 Excellent
"All in all, wasn't too bad. Is time for some renovation."
David 1-night trip
Posted 2 days ago
Quality Inn Cape Girardeau North
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

8/10 Good
"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."
Valarie 2-night trip
Posted 2 weeks ago
Hampton Inn Cape Girardeau I 55 East
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent
"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."
Sheila and keith 1-night trip
Posted 2 weeks ago
Courtyard by Marriott Cape Girardeau Downtown
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

8/10 Good
"The outside needed cleaning, but the room was very clean and well maintained."
Michael p 1-night trip
Posted 1 month ago
Town House Inn Cape Giradreau

Frequently asked questions

How much does a hotel room cost in Cape Girardeau?
You can choose a great hotel in Cape Girardeau from NZ$120 with properties to suit all budgets and needs. Pear Tree Inn Cape Girardeau West is one low-cost option that's popular with our travellers. If you're looking for an affordable hotel in Cape Girardeau that meets all of your requirements, just sort hotels by "Price: low to high" after applying your filters when searching on Hotels.com.
How can I find deals and earn rewards at Cape Girardeau hotels?
Discover great deals on Cape Girardeau hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Cape Girardeau hotels.
Can I book Cape Girardeau hotels with free cancellation?
In order to book a refundable Cape Girardeau hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some top pet-friendly hotels in Cape Girardeau?
Our travellers' favourite pet-friendly hotels in Cape Girardeau include:You can also use the "Amenities" filter in your search on Hotels.com and check "Pet friendly" to discover more pet-friendly hotels in Cape Girardeau.
What are some of the best hotels in Cape Girardeau for couples?
Choose a top-rated Cape Girardeau romantic hotel and enjoy your couple's getaway. Our travellers love The Riverview, a hotel with 2 restaurants as well as champagne service. Discover more hotels in Cape Girardeau on Hotels.com for couples by using the "Traveller experience" filter in your search and selecting "Adults only" or "Romantic".
What are the top Cape Girardeau hotels with a pool?
For some added luxury, discover the best Cape Girardeau hotels with a pool. Drury Plaza Hotel Cape Girardeau Conference Center is a great hotel with an indoor pool and a guest rating of 9.6 out of 10. Drury Inn & Suites Cape Girardeau is a popular hotel that features an indoor pool along with a hot tub and a free buffet breakfast. To find more stays in Cape Girardeau with a pool, use the "Amenities" filter on Hotels.com in your search and select "Pool".
What are some of the best Cape Girardeau hotels with free parking?
If you're exploring by car, finding a great Cape Girardeau hotel with free parking is a win. Our travellers' favourites include:
What are some popular hotels in central Cape Girardeau?
For hotels in central Cape Girardeau, check out Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott Cape Girardeau Downtown. Travellers love Drury Plaza Hotel Cape Girardeau Conference Center for its location, as well as the indoor pool, hot tub and restaurant this hotel offers. Courtyard by Marriott Cape Girardeau Downtown is another popular central hotel with a restaurant, a bar/lounge and a coffee shop/cafe.
Can I book a refundable accommodation option in Cape Girardeau?
If you want the flexibility to change your plans to Cape Girardeau, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Cape Girardeau if I want a holiday rental instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 30 holiday homes. In addition, you can choose from 20 apartments.
What will the weather in Cape Girardeau be like during my visit?
July and August are typically the warmest months in Cape Girardeau, when the average temperature is 25°C. January and February are the coldest months, when the average temperature is 5°C. April and March are the months with the most rain.
Why should I book my Cape Girardeau hotel with Hotels.com?
There are lots of reasons to book your Cape Girardeau trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.

Find out more about Cape Girardeau

Explore Cape Girardeau: Where River Serenity Meets Floral Splendor and Academic Vibrance

Nestled along the banks of the mighty Mississippi River, Cape Girardeau, Missouri, is a hidden gem that beautifully blends history, nature, and culture. Stroll through the charming downtown, where historic architecture meets vibrant art galleries and delightful eateries. Explore the scenic Riverfront Park, perfect for leisurely walks, picnics, and stunning river views. Don’t miss the Cape Riverfront Market for local produce and crafts. For sports enthusiasts, the Cape Girardeau Sportsplex offers various activities. With its welcoming atmosphere and rich heritage, Cape Girardeau invites you to experience a delightful blend of small-town charm and captivating adventures.

4 tips for savvy savings when booking a hotel in Cape Girardeau

  1. Book for the cheapest times: The most budget-friendly time to visit Cape Girardeau is during January, November, and December, when hotel prices are generally lower. For an affordable experience that allows you to soak in the region's historical and cultural highlights, a stay of at least 2 to 3 days is recommended. This will give you ample time to explore key landmarks, such as the river, as well as enjoy family-friendly activities, historical sites, and the vibrant dining and shopping scene. You'll also appreciate the friendly locals and the charming atmosphere, making your visit truly great value for money.
  2. Look for last-minute deals on Hotels.com: To uncover affordable hotel options in Cape Girardeau, start by exploring the DealsOpens in a new window or Last-Minute Deals sections on Hotels.com, where you may discover discounted rates as your travel date approaches. Consider enabling email alerts or push notifications to keep informed about flash sales and special last-minute offers, ensuring you don’t miss potential savings. Additionally, the Smart Shopping tool in the app allows you to compare hotel prices and amenities, helping you make informed choices. This way, if prices drop or rooms become available, you're more likely to see these updates first, making your last-minute getaway planning easier.
  3. Be flexible with dates: Prices can fluctuate depending on factors like the hotel's location, star rating, and the time of year. Being flexible with your travel dates could help you potentially save on your stay at a hotel in Cape Girardeau. If you're after a unique experience, boutique hotels often provide a more personalised touch and may offer better value. When you book through Hotels.com, we’ll inform you whether the price for your chosen dates is above or below the average. If the price leans towards the higher end, we’ll suggest alternative dates that could be more affordable, helping you to secure a better deal.
  4. Consider your location: Hotels close to the city centre usually tend to be more expensive, but with Cape Girardeau's excellent public transport connections, you may discover a more affordable independent hotel a bit further out that is still well connected. For those keen to explore alternative, less crowded neighbourhoods or even some lesser-known nearby towns, there is often great value for money to be found. Opting for these alternative destinations could provide a more authentic and budget-friendly experience.

Best time to go to Cape Girardeau

Cape Girardeau experiences its lowest average temperature in January, at 34.9°F (1.6°C), while July is the hottest month, with an average temperature of 79.2°F (26.2°C). April tends to be the wettest month. The peak travel months to visit Cape Girardeau are April, June, and July, which see a higher number of tourists. During this peak period, the weather is mostly sunny, accompanied by light rainfall. In contrast, January, October, and December are ideal if you're looking for a calmer vacation, marked by light rainfall and mostly sunny conditions.

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