If you're looking for a place to get away, look no further than Cayo Guillermo. Whether you're planning to stay for a night or for the week, the area around Cayo Guillermo has accommodation options to fit every need. Search for hotels in Cayo Guillermo with Hotels.com by checking our online map. Our map displays the areas and neighbourhoods around all Cayo Guillermo hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Cayo Guillermo hotel deals are here with our lowest price guarantee.
Cayo Guillermo Hotels with Smoking Rooms Facilities
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Cayo Guillermo Hotels with Smoking Rooms Facilities
Top landmarks in Cayo Guillermo
Cayo Guillermo Beach
If being by the water is a major draw, Cayo Guillermo Beach is a spot you might want to check out, located 2.1 mi (3.4 km) from central Cayo Guillermo.
Cayo Guillermo Marina
Cayo Guillermo Marina is worth a visit, located 2.6 mi (4.2 km) from central Cayo Guillermo.
Find out more about Cayo Guillermo
Find out more about Cayo Guillermo
Keep exploring
Keep exploring
- Hotels in Havana
- Hotels in Varadero
- Hotels in Cárdenas
- Hotels in Cayo Coco
- Hotels in Trinidad
- Hotels in Cayo Santa Maria
- Hotels in Holguín
- Hotels in Viñales
- Hotels in Cienfuegos
- Hotels in Guardalavaca
- Hotels in Santiago de Cuba
- Hotels in Venezuela
- Hotels in Santa Clara
- Hotels in Cayo Largo
- Hotels in Camaguey
- Hotels in Matanzas
- Hotels in Ciénaga de Zapata
- Hotels in Santa Lucia
- Hotels in Playa Pesquero
- Hotels in Moron