If you're looking for a place to get away, look no further than Big Pine Key. Whether you're planning to stay for a night or for the week, the area around Big Pine Key has accommodations to fit every need. Search for hotels in Big Pine Key with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Big Pine Key hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Big Pine Key hotel deals are here with our lowest price guarantee.