South Carolina Lowcountry Hotel Accommodation

your current months are January, 2025 and February, 2025.
January 2025
February 2025

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Free cancellation options if plans change

Where to stay in South Carolina Lowcountry?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in South Carolina Lowcountry

Top landmarks in South Carolina Lowcountry

Learn more about South Carolina Lowcountry

South Carolina Lowcountry is applauded for its cultural attractions such as Penn Center and Highway 21 Drive-In Theater.

Photo by Hilton Head Island Visitor & Convention Bureau
Open Photo by Hilton Head Island Visitor & Convention Bureau

Frequently asked questions

Can I book a refundable accommodation option in South Carolina Lowcountry?
If you want the flexibility to change your plans to South Carolina Lowcountry, most hotels offer refundable* rates that you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in South Carolina Lowcountry if I want a holiday rental instead of a hotel?
If you’re looking for a good alternative to a hotel, browse our selection of 4188 holiday homes. In addition, there are 225 apartments and 3043 condos.
Why should I book my South Carolina Lowcountry hotel with Hotels.com?
There are lots of reasons to book your South Carolina Lowcountry trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures that you always get the lowest price, and you can earn rewards on every booking.